Tumor lysis syndrome after sorafenib for hepatocellular carcinoma
نویسندگان
چکیده
منابع مشابه
Tumor lysis syndrome following sorafenib treatment in hepatocellular carcinoma
Sorafenib is indicated for the treatment of advanced hepatocellular carcinoma (HCC), but although rare, tumor lysis syndrome (TLS) can be fatal in HCC patients with a large tumor burden. The authors describe the case of a 55-year-old hepatitis B carrier who visited our clinic with progressive dyspnea for 3 weeks. Chest and abdominal computed tomography revealed a huge HCC in the left lobe of th...
متن کاملSorafenib in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the fi fth most common malignancy worldwide with approximately 500,000 new cases per year, ranking as the third cause of cancer deaths. Until the very recent past no systemic therapy was available for patients with advanced HCC. However, advances achieved in the understanding of the molecular cancer biology and the subsequent introduction of molecularly targete...
متن کاملSorafenib for recurrent hepatocellular carcinoma after liver transplantation.
OBJECTIVE Sorafenib is the only drug that has shown a survival benefit in patients with hepatocellular carcinoma in randomized Phase 3 trials. The efficacy and safety of sorafenib in the treatment of recurrent hepatocellular carcinoma after liver transplantation, however, has not been determined. METHODS We retrospectively analyzed 13 patients who were treated with sorafenib for recurrent hep...
متن کاملRasburicase for huge hepatocellular carcinoma with tumor lysis syndrome: case report.
OBJECTIVE To report a case of huge hepatocellular carcinoma associated with tumor lysis syndrome and its management. CLINICAL PRESENTATION AND INTERVENTION A 51-year-old hepatitis B carrier visited our clinic with progressive weight loss over recent months. Abdominal ultrasonography and magnetic resonance imaging revealed a huge hepatic mass in a cirrhotic liver, identified as hepatocellular ...
متن کاملSorafenib in advanced hepatocellular carcinoma.
BACKGROUND No effective systemic therapy exists for patients with advanced hepatocellular carcinoma. A preliminary study suggested that sorafenib, an oral multikinase inhibitor of the vascular endothelial growth factor receptor, the platelet-derived growth factor receptor, and Raf may be effective in hepatocellular carcinoma. METHODS In this multicenter, phase 3, double-blind, placebo-control...
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ژورنال
عنوان ژورنال: Kanzo
سال: 2014
ISSN: 0451-4203,1881-3593
DOI: 10.2957/kanzo.55.228